Research review - The Protective Role of Astaxanthin for UV-Induced Skin Deterioration in Healthy People
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Summary
The skin is a primary protective tissue in humans. Since the function of the biological barrier is degraded by several types of stress (oxidative stress) for example exposure to ultraviolet (UV) rays, the protection and treatment of skin conditions by taking nutritional supplements is very important.
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We therefore evaluated the effects of dietary supplements with an antioxidant derived from algae food, astaxanthin, on skin deterioration caused by UV exposure.
Twenty-three healthy Japanese participants were recruited into a 10-week, double-blind, placebo-controlled study. They were assigned to the astaxanthin group plus a capsule containing 4 mg of astaxanthin or the placebo group.
To assess the role of astaxanthin in protecting the skin against UV-induced deterioration, we determined the minimal erythema dose (MED) and analyzed UV-induced changes in moisture and transepidermal water loss (TEWL) at baseline and after 9 weeks of addition.
Subjective skin conditions were assessed by a visual analog scale. The astaxanthin group showed an increased MED compared to placebo. In addition, the astaxanthin group had a reduced loss of skin moisture in the irradiated area compared to placebo. Subjective skin conditions for "roughness improvement" and "texture" in non-irradiated areas were significantly improved by astaxanthin.
In conclusion, Astaxanthin appears to be a significant protector against skin damage caused by solar radiation (UV) and helps maintain healthy skin in healthy people.
Keywords: astaxanthin, antioxidant, skin, ultraviolet, UV, MED, moisture
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